Mixoma cardiaco como causa de isquemia en niños. Reporte de casos

El mixoma cardiaco constituye uno de los tumores benignos más frecuentes entre los tumores cardiacos. El mismo se caracteriza por la obstrucción del flujo sanguíneo por trombosis o émbolo, resultando en causa de insuficiencia cardiaca con disfunción ventricular, síncope ortostático, isquemia de diferentes órganos de acuerdo a la arteria afectada, e incluso muerte súbita. Presentamos 2 casos en pacientes pediátricos: el primer caso, una adolescente con ACV isquémico y el segundo caso se trata de un adolescente con isquemia a nivel de miembros inferiores por una tromboembolia en la Aorta distal. En ambos casos se realizó la exéresis del tumor, con éxito.

Cardiac myxoma is one of the most frequent benign tumors among cardiac tumors. It is characterized by the obstruction of blood flow due to thrombosis or embolus, resulting in heart failure with ventricular dysfunction, orthostatic syncope, ischemia of different organs depending on the affected artery, and even sudden death. We present 2 cases in pediatric patients: the first case, an adolescent with ischemic stroke and the second case is an adolescent with ischemia in the lower limbs due to a thromboembolism in the distal aorta. In both cases, the exeresis of the tumor was performed successfully.

A Case of Decreased Swallowing Function Due to Cardiac Myxoma / 日本プライマリ・ケア連合学会誌

The case was a 77-year-old man. He had dizziness and dysphagia for 2 years, and underwent detailed screening at the internal medicine department for general malaise and bloody sputum. He was hospitalized for aspiration pneumonia due to dysphagia of unknown origin. This time, he visited a local doctor with palpitations and shortness of breath. Echocardiography indicated a left atrial tumor involving the mitral valve and arrhythmia. Emergency surgery was performed to remove the left atrial myxoma and close the patch at our hospital's cardiovascular surgery department. After the excision, swallowing function was restored, and the patient was diagnosed with postoperative Ortner's syndrome. We report a case where echocardiography was considered important as a detailed investigation of the cause of swallowing dysfunction and dizziness.

Minimal invasive surgical resection of myxomas: a three case series study / Resección quirúrgica mínimamente invasiva de mixomas: estudio de tres casos

Abstract Introduction and Objective Cardiac tumors are often unrecognized until autopsies are performed or diagnosed from routine studies based on unspecific symptoms. The most common type of tumor is the myxoma, although rare, upon diagnosis an urgent surgical resection is often required. Previously the ideal surgical approach was a standard median sternotomy, however recently newer surgical techniques have been employed with excellent results. We describe a recent surgical approach via the right lateral minithoracotomy as a minimally invasive intervention with three cases that evidence an appropriate and ideal surgical approach. Method and Patients We present three cases of minimally invasive myxoma resection via the right lateral minithoracotomy. Results and discussion In this three-case series study, no complications were reported peri-operatively nor at the 6 and 12-month follow-ups. In comparison with international literature, surgical approaches in Colombia are comparable with successful resection and little or no complications peri-operatively. Conclusions The right lateral minithoracotomy appears to be a safe approach in myxoma resection. We hope to enhance and promote the surgical community in Colombia to opt for alternative less invasive approaches in these type of cases, to ensure excellent results and promote further research as seen in other countries.

Resumen Introducción y Objetivo Los tumores cardíacos no suelen ser diagnosticados hasta la realización de autopsia o en otros casos como hallazgos incidentales. El tumor cardiaco más común es el mixoma, aunque es poco frecuente; en el momento del diagnóstico a menudo se requiere una resección quirúrgica urgente. Anteriormente el enfoque quirúrgico era una atriotomía abierta derecha; sin embargo, recientemente se han empleado técnicas quirúrgicas nuevas con excelentes resultados. Describimos una técnica quirúrgica reciente a través de la minitoracotomía lateral derecha como un método mínimamente invasivo con tres casos que evidencian un método quirúrgico apropiado e ideal. Métodos y pacientes: Se presentan tres casos de resección mínimamente invasiva de mixomas a través de una minitoracotomía lateral derecha. Resultados y discusión: Es estos tres casos no se reportaron complicaciones perioperatorias ni durante el seguimiento a los 6 y 12 meses. En comparación con otras series de casos en la literatura, el enfoque en Colombia ha sido comparable tanto en los resultados exitosos como con las técnicas quirúrgicas, sin complicaciones asociadas. Conclusiones La minitoracotomía lateral derecha puede ser considerada segura en resección de mixoma. Con este tipo de reportes se espera suscitar en la comunidad médica la elección de alternativas quirúrgicas mínimamente invasivas para garantizar excelentes resultados y promover la investigación, como se evidencia en el resto del mundo.

Multiple cerebral aneurysms originating from previously resected cardiac myxoma

Primary cardiac tumors are very rare, accounting for 0,001 ­0,03% in autopsy series, cardiac myxoma (CM) account for approximately 50% of them. Association between CM and cerebral aneurysm is well documented in this condition but the occurrence of cerebral aneurysm after resection of CM is very rare, with only 40 reports in medical literature. We present a case of a 45 years old female patient with multiple cerebral aneurysms 2 years after a successful resection of cardiac myxoma, submitted to radiosurgery for 2 bigger aneurysms with good results. This report ads to literature new clinical findings and a hypothesis of radiosurgery as an effective option of treatment for cerebral aneurysms with origin in CM. Keywords: Cardiac Myxoma; Cerebral aneurysm; Radiosurgery; Neurosurgery.

Reoperation for cardiac myxoma: report of 23 cases / 中华胸心血管外科杂志

Objective:To summarize the experience of reoperation for 23 cases of cardiac myxoma recurrence.Methods:From January 2002 to December 2018, 1106 patients with cardiac myxoma underwent surgical treatment. Among them, 23 patients underwent reoperation after recurrence. 10 males and 13 females with an average age of (50.5±10.8) years old. There were 22 patients with secondary operation and 1 patient with four operations. 3 cases with mitral insufficiency and 1 case with tricuspid insufficiency. There were 20 patients with NYHA Ⅰ-Ⅱ and 3 patients with Ⅲ-Ⅳ. A total of 1 083 patients with cardiac myxoma undergoing primary operation were selected as the control group. The operation time, cardiopulmonary bypass time, aortic clamping time, ICU monitoring time, ventilator assisted breathing time, postoperative hospital stay, in-hospital mortality and cardiac ejection fraction at discharge were compared between the two groups.Results:8 cases (34.8%) had the first onset in the left atrial septum, and 15 cases (65.2%) in other parts. Recurrence site: left atrium in 17 cases(73.9%), left ventricle in 2 cases (8.7%), right atrium in 3 cases (13.0%), right ventricle in 1 case (4.3%). Reoperation accounted for 2.1% of cardiac myxoma surgery in the same period. The median recurrence time of 13 patients was 24 months. During the same period, mitral valve replacement was performed in 2 cases, mitral valvuloplasty in 1 case and tricuspid valve plasty in 1 case. The average operation time was (3.9±2.8) h, cardiopulmonary bypass time was (107.6±33.8) min, aortic clamping time was (64.9±23.8) min, ICU monitoring time was (20.1±16.0) h, ventilator assisted breathing time was (16.9±8.5) h, cardiac ejection fraction at discharge was 0.51±0.10, postoperative hospital stay was (8.3±1.5) days. The median follow-up time was 5 (1-18) years. One case (4.3%) died of all causes. There was no significant difference in ICU monitoring time, ventilator assisted breathing time, discharge cardiac ejection fraction, postoperative hospital stay and hospital mortality between reoperation patients and one operation ( P>0.05). Conclusion:Atypical cardiac myxoma has a high recurrence tendency after operation. Regular follow-up after the first operation of cardiac myxoma is a necessary means to early detect recurrence and avoid complications. Reoperation after recurrence can still achieve satisfactory results.

Clinical presentation of cardiac myxoma in a Singapore national cardiac centre

INTRODUCTION@#Cardiac myxoma is the most common cardiac tumour. In this study, we summarise our 17-year experience with the clinical presentation of cardiac myxoma at National Heart Centre Singapore, Singapore.@*METHODS@#Between January 2000 and December 2016, retrospective data was reviewed for all consecutive patients who underwent surgical resection of cardiac myxoma. Patients' clinical characteristics were reviewed and described.@*RESULTS@#A total of 67 (18 male, 49 female; mean age 53.1 ± 13.5 years) patients underwent cardiac myxoma resection. There were 19 (28.4%) patients with asymptomatic cardiac myxoma. There were no significant differences in gender; body habitus and myxoma size; and haemoglobin, white blood cell or platelet counts between patients with symptomatic and asymptomatic myxoma. However, the number of asymptomatic cardiac myxomas seemed to follow an increasing trend from 19.4% (period 2000-2008) to 36.1% (period 2009-2016), suggestive of an 'era effect'.@*CONCLUSION@#In our study, a majority of patients were women, with a wide age range of 18-78 years. The diagnosis of asymptomatic cardiac myxoma was present in 28.4% of patients, with an increasing trend for incidence over the years. This is possibly due to increased opportunistic screening (with electrocardiography and clinical examination) as well as higher usage of medical imaging.

Variabilidad de síntomas del mixoma cardíaco / Variability of Symptoms of Cardiac Myxoma

Introducción: De los tumores cardiacos primarios, más del 50 por ciento son mixomas. La variabilidad sintomática del mixoma cardiaco, puede llevar a confusiones diagnósticas. Objetivo: Presentar un caso donde se destaca la variabilidad de síntomas del mixoma cardíaco. Caso clínico: Paciente masculino de 51 años, atendido con manifestaciones de insuficiencia cardíaca, trastornos del ritmo cardíaco, micro embolias cerebrales, convulsiones tónico clónicas, hemoptisis, trastornos psiquiátricos, síndrome general con astenia, anorexia y pérdida de peso. Durante dos años, fue atendido en varias instituciones, con múltiples estudios y tratamientos. En el Servicio de Cardiología de Morón, Ciego de Ávila, mediante el estudio clínico y ecocardiográfico, se diagnosticó un tumor cardíaco. Se traslada al Cardiocentro de Santa Clara y allí se le extirpó el tumor. Histológicamente era un mixoma. Evolucionó muy bien, con excelente calidad de vida. Conclusiones: El mixoma cardíaco ocasiona síntomas obstructivos, embólicos y constitucionales, con cuadro clínico muy equívoco(AU)

Introduction: Of the primary cardiac tumors, more than 50 percent are myxomas. Symptomatic variability of cardiac myxoma can lead to diagnostic confusion. Objective: To present a case where the variability of cardiac myxoma symptoms is highlighted. Clinical case: A 51-year-old male patient, attended with manifestations of heart failure, heart rhythm disorders, micro cerebral embolisms, clonic tonic seizures, hemoptysis, psychiatric disorders, general syndrome with asthenia, anorexia and weight loss. For two years, he was treated in several institutions, with multiple analyses and treatments. In the Cardiology Department of Morón, Ciego de Ávila, through a clinical and echocardiographic study, a cardiac tumor was diagnosed. He moved to the Cardiocentro of Santa Clara and there, the tumor was removed. Histologically it was a myxoma. It evolved very well, with excellent quality of life. Conclusions: Cardiac myxoma causes obstructive, embolic and constitutional symptoms, with a very equivocal clinical picture(AU)

Clinical analysis of cardiac myxoma leading to embolic events / 中国胸心血管外科临床杂志

@#Objective    To investigate the clinical manifestations of patients with cardiac myxoma and the factors affecting the occurrence of embolic events. Methods     A retrospective study of 38 patients with cardiac myxoma diagnosed and surgically removed from January 2010 to December 2017 was performed. There were 11 males and 27 females at age of 32-75 (50.00±16.12) years. The patients were divided into a non-embolized group and an embolized group. The clinical manifestations of the patients were summarized and the factors leading to embolism were analyzed. Rseults    Of the 26 patients in the non-embolized group, 22 patients (84.62%) had dyspnea, 14 patients (53.85%) had palpitations, 4 patients (15.38%) had angina pectoris, and 1 patient (3.85%) had heart failure. Of the 12 patients in the embolized group, 4 patients (33.33%) had dyspnea, 3 patients (25%) had palpitations, and 1 patient (8.33%) had angina pectoris. The mean diameter of the non-embolized group was 5.71±1.63 cm, and the maximum diameter of the tumor in the embolized group was 4.52±1.88 cm. There was no significant difference between the maximum diameter of the tumor in the embolized group and the maximum diameter of the non-embolized group (P>0.05). Atrial fibrillation occurred in 2 patients in the non-embolized group before operation. Atrial fibrillation occurred in 5 patients in the embolized group. Atrial fibrillation was more likely to occur in the embolized group (P<0.05). Conclusion     Atrial fibrillation in the patients with cardiac myxoma is closely related to embolic events. The size of myxoma is not related to the occurrence of embolic events.

Manejo quirúrgico del mixoma cardíaco / (Surgical management of cardiac myxoma)

ResumenSe presenta el caso de una paciente de 32 años, con trastorno psiquiátrico, con historia de un mes de evolución de disnea y tos no productiva, tratada inicialmente como bronconeumonía, con amplia cobertura antibiótica sin mejoría de síntomas; se maneja luego como síndrome de dificultad respiratoria aguda. Debido a franco ataque al estado general y datos incongruentes con historia clínica, se realiza ecocardiograma que incidentalmente reporta mixoma en aurícula izquierda. Los mixomas cardíacos son el tipo más común de tumores primarios benignos cardíacos, una patología poco frecuente y con mortalidad asociada a muerte súbita en un 15%. La mayoría de casos son encuentros incidentales, esporádicos y su etiología no es conocida. Los síntomas pueden asociarse a embolismo del tumor, insuficiencia cardiaca, obstrucción mecánica valvular y síntomas constitucionales varios.

AbstractWe present the case of a 32 year old patient known to have a psychiatric disorder, who presented with a history of one month of dyspnoea and nonproductive cough, which was treated initially as bronchopneumonia, with wide spectrum antibiotics without clinical improvement. Later is treated as an acute pulmonary distress syndrome, but because of poor general condition and incongruent data in the clinical history an echocardiogram was performed in the Emergency Room that incidentally founds a myxoma in the left atrium. Cardiac myxomas are the most common primary heart benign tumors, and have a mortality rate associated with sudden death of 15%. In the majority of the cases the diagnosis is incidental, sporadic and the etiology is unknown.The symptoms may be associated with tumor embolism, heart failure, valvular disease and nonspecific symptoms.

Mixoma cardiaco materno durante el embarazo / Maternal cardiac myxoma during pregnancy

Los mixomas cardiacos pueden producir complicaciones graves en las embarazadas. Los hallazgos clínicos dependen de la localización, tamaño y movilidad. Embolismos, obstrucción intracardiaca y síntomas constitucionales pueden ser la presentación inicial. La resección quirúrgica es el tratamiento definitivo. Solo se ha comunicado previamente veinte casos y se reporta un caso de mixoma cardiaco en una embarazada quien asistió a la consulta de Cardiología a las 30 semanas con un ecocardiograma que reportaba una tumoración en el ventrículo izquierdo. La cesárea electiva fue realizada a las 34 semanas y el bypass cardiopulmonar y la resección del mixoma ocurrieron 5 días después. Esta potencial condición perjudicial reseña la importancia de considerar este raro problema médico que puede presentarse durante el embarazo.

Atrial myxomas may cause serious disability in pregnant women. Clinical features depend on location, size and mobility. Embolism, intracardiac obstruction and constitutional symptoms may be the initial presentation. Surgical excision is the definitive treatment. Only twenty cases have been previously published. We report a case of a cardiac myxoma in a pregnant patient who attended the cardiology service at 29 weeks of gestation where the echocardiogram revealed a mass in the left atrium. Elective caesarean section was performed at 34 weeks. Five days later, cardiopulmonary bypass surgery and excision of myxoma five days later. This potentially life-threatening condition highlights the importance of considering of rare medical problems presenting during pregnancy.

The clinical characteristics of stroke in young patients with cardiac myxoma / 中华内科杂志

Objective To investigate the clinical characteristics of stroke in young patients with cardiac myxoma.Methods Medical records of young patients (aged between 18-44 years) diagnosed with cardiac myxoma in Beijing Anzhen Hospital affiliated to Capital Medical University from January 2005 to March 2016 were retrospective reviewed.Results A total of 117 cases were included (85 female and 32 male)with the average age (36 ±7)years old.Most myxomas (83.8％) were located in the left atrium,7.7％ were in the right atrium,3.5％ were in the both atriums,2.6％ were in the left ventricle,and a few were in the left atrium plus left ventricle and in the right ventricle.Of all the patients,24 (20.5％) (16 women and 8 men) were complicated with cerebral infarction.Among them,3 patients were with lower extremity arterial embolisms.Two patients were with cerebral hemorrhage.The cerebral infarction mainly involved in the distribution area of the internal carotid artery.Infarctions involving 2 or more cerebral vessels were found in 4 cases.Most subjects (58.3％) manifested with hemiplegia,and some (18.2％) with syncope.The proportion of the left atrial myxoma in patients with cerebral infarction (100.0％) was significantly higher than those in patients without cerebral infarction (85.1％,P =0.044).Subjects with tumor diameter less than 3 cm were more frequently complicated with cerebral infarction (37.5％ vs 13.8％,P =0.009).A logistic analysis showed that the odds ratio of myxoma with tumor diameter less than 3 cm for cerebral infarction was 3.750 (95％ CI 1.343-10.470).Conclusions Cardiac myxoma is more common in young women,and often complicated with cerebral infarction.The infarctions are mainly distributed in internal carotid artery system,and some are involved in multiple vascular systems.The incidence of stroke is associated with the position of the myxoma.Smail-size myxoma cannot be ignored for its risk of stroke.

A Case Report of Central Retinal Artery Occlusion Caused by Cardiac Myxoma

PURPOSE: We report the case of a patient diagnosed with central retinal artery occlusion caused by cardiac myxoma who underwent surgery to remove the myxoma. CASE SUMMARY: A 47-year-old woman came to our clinic presenting with a sudden decrease of visual acuity in the left eye. At the first visit, left eye visual acuity was hand motion, and intraocular pressure was 15.4 mmHg. A relative afferent pupillary defect was observed in the left eye. On fundus examination, a pale retina and cherry-red spot were observed at the posterior pole. On optical coherence tomography, macular edema was found. On fluorescein angiography and indocyanine green angiography, delayed blood circulation of the retina and choroid was found at early and late stages. Cerebral angiography was performed in the neurosurgery department and showed no occlusion of the ophthalmic artery. Cardiac ultrasonography and brain magnetic resonance imaging were performed. On cardiac ultrasonography, 4.46 × 2.09 cm cardiac myxoma was found. Resection of the cardiac myxoma was conducted in the thoracic and cardiovascular surgery department. Multiple cerebral infarcts were detected by brain imaging, and antithrombotic treatment was administered. After one month, blood circulation in the retina and choroid was observed in fluorescence angiography, but there was no improvement of visual acuity. At the 3-month follow-up visit, macular edema was decreased, but retinal atrophy and epiretinal membrane were observed on optical coherence tomography. CONCLUSIONS: Central retinal artery occlusion is a disease related to one's general condition. We experienced this case of central retinal artery occlusion caused by cardiac myxoma.

Evaluation of Multi-slice CT and Echocardiography in Diagnosing Multiple Cardiac Myxoma Originated From Special Site of the Heart / 中国循环杂志

Objective: To explore the necessity of multi-slice CT (MSCT) and echocardiogram in diagnosing multiple cardiac myxoma or myxoma originated from special site of heart via analyzing medical imaging features. Methods: A total of 14 patients with multiple cardiac myxoma or myxoma not originated from left atrium fossa ovale were studied; the patients had operation conifrmed diagnosis in our hospital from 2003-02 to 2015-12, the imaging features of MSCT and echocardiography were analyzed and compared. Results: There were 12/14 patients diagnose by echocardiography with the accuracy of 85.7% and 11 patients diagnosed by MSCT with the accuracy of 84.6%. MSCT and echocardiography had similar pre-operative accuracy and complimentary advantages for diagnosing multiple cardiac myxoma or myxoma not originated from regular site of heart. Echocardiography was superior for examining the motion, pedicle position, shape and attachment point of cardiac myxoma; MSCT may exclude pulmonary embolism and coronary artery disease at meanwhile. Conclusion: Unconventional cardiac myxoma not only has similar image signs to typical single myxoma from left atrium, but also has the speciifc features; MSCT combining echocardiogram examinations could make more accurate diagnosis and provide a better condition for surgical treatment.

Coexistence of Acute Cerebral Infarction and Peripheral Embolism in a Patient with Cardiac Myxoma

There are rare reports of vascular complications in patients with cardiac myxoma, including both central and peripheral arterial thrombosis. We report on a patient with cerebral infarctions affecting multiple territories, which may have been related to cardiac myxoma. The patient also exhibited cyanosis of the hand. A diagnosis was made of peripheral artery occlusion with myxomatous emboli. A careful physical examination with suspicion of concomitant peripheral embolism is needed in patients with acute embolic stroke induced by cardiac myxoma.

Distinctive Patterns of MRI in Cerebral Embolism Caused by Cardiac Myxoma

While cardiac myxoma is a rare cause of stroke, it needs to be considered so that it can be detect promptly. We report the magnetic resonance imaging (MRI) characteristics of three patients who were histologically confirmed as cardiac myxoma. MRI revealed multiple infarctions in bilateral hemispheres and hemorrhagic transformation including microbleeds and macrobleeds. If either petechial hemorrhage or microbleeds along the cortical border zone are identified in MRI of acute stroke patients, the possibility of cardiac myxoma should be considered.

Cutaneous myxoma: An important clue to Carney complex.

A 22-year-old male became unconscious and was found to have left-sided weakness and facial asymmetry. Previously, he had up to 35 excisions for subcutaneous swellings all over the body, commencing at age 6 years. Examination revealed small nodular skin lesions on the neck, the eyelid and hard palate. Two-dimensional echocardiography showed two left atrial masses. Histopathological examination of the subcutaneous lesions showed cutaneous myxomas with a prominent epithelial component. The left atrial masses were also myxomas. The case attempts to highlight the importance of histopathological examination of subcutaneous swellings. Cutaneous and subcutaneous manifestations, including cutaneous myxomas, are among the earliest presentations in Carney’s complex and may herald potentially fatal cardiac myxoma. The prominent epithelial component in cutaneous myxomas may be confusing and cause diagnostic difficulties.

Left Atrial Intramural Hematoma after Removal of Atrial Myxoma: Cardiac Magnetic Resonance in the Differential Diagnosis of Intra-Cardiac Mass

Left atrial (LA) dissection is a rare entity, which is, in most cases, observed after valvular intervention. Transesophageal echocardiography (TEE) is considered to be a modality of choice in the diagnosis of LA dissection. However, LA dissection might be missed clinically in the absence of significant hemodynamic changes, and moreover physicians are occasionally reluctant to perform TEE due to its semi-invasiveness. Recently, cardiac magnetic resonance (CMR) has been introduced as a modality to perform different roles to existing imaging modalities, such as echocardiography. Given that CMR can provide information on tissue characteristics, it may give incremental information to TEE. We here present a rare case of LA dissection following LA myxoma removal, where CMR can make a correct diagnosis and guide management strategy.

Metástasis cerebral de mixoma cardíaco. reporte de un caso y revisión literaria / Cerebral metastasis of myxoma. case report and literary review

Introducción: el mixoma, es el tumor cardiaco benigno más frecuente, su resección quirúrgica suele ser curativa. En la literatura se han relatado casos de recidiva tumoral y pocos casos de metástasis. Reportamos un caso de metástasis cerebral múltiple de mixoma cardiaco como debut clínico de este tumor. Descripción del caso: presentamos el caso de una mujer de 42 años, que debuta con un cuadro de amaurosis fugax. En las pruebas de imágenes craneales se observó la presencia de múltiples lesiones cerebrales. Se amplió el estudio observándose la presencia de una masa a nivel auricular izquierda. La paciente fue intervenida de la masa cardiaca obteniéndose el resultado de mixoma. Posteriormente se realizó la extirpación de una las lesiones a nivel craneal, para obtener el diagnóstico. El resultado tras la exéresis quirúrgica es de metástasis cerebral de mixoma cardiaco. Discusión: se discute en este artículo, las distintas formas de presentación del mixoma cardiaco a nivel cerebral, así como el manejo terapéutico. Conclusión: el debut clínico de unas metástasis cardiacas con clínica neurológica, es una forma muy inusual de presentación en esta patología, dado que la presencia de una metástasis cerebral de mixoma cardiaco es muy poco frecuente, de ahí el interés que presenta este caso clínico.

Introduction: the myxoma is the most common benign cardiac tumor, surgical resection is usually curative. In the literature have reported cases of tumor recurrence and metastasis few cases. We report a case of multiple brain metastases of cardiac myxoma as clinical onset of this tumor.Development: we report the case of a woman of 42, who debuted with a picture of amaurosis fugax. In cranial imaging tests showed the presence of multiple brain lesions. Expanded study observed the presence of a left atrial mass level. The patient was operated on cardiac mass to give the result of myxoma. Later the removal of a cranial lesions level to obtain the diagnosis. The outcome following surgical resection of brain metastases is of cardiac myxoma.Discussion: We discuss in this article, the various forms of presentation of cardiac myxoma in the brain, and therapeutic management. Conclusion: the clinical onset of a cardiac metastases with neurological symptoms, is a very unusual form of presentation in this disease, since the presence of a brain metastasis of cardiac myxoma is rare, hence the interest of this case report.

Brain Metastasis of Atrial Myxoma: Case report

Metastasis of an atrial myxoma to the brain is extremely rare1. Thus far there are only 17 cases reported, including our present case. Most of the brain metastases manifest only in 3 to 6 decades, after an average time frame of one to two years after surgical removal of parental tumour. We present a case of brain metastases of atrial myxoma in a teenager of the youngest age among all reported cases, unusually as early as 15 years old 3. The progress of the metastatic process had been insidious for three years after heart surgery, The imaging demonstrated a rather sizeable tumour by the time when the patient is symptomatic. The location of the metastatic tumour is anyhow superficial to the cortical surface, enabling complete surgical excision of the tumour easily achievable with favourable outcome.

Cardiac Myxoma Diagnosed by Signs of Purpuric Macules on Both Palms and Soles

Cardiac myxoma, the most prevalent primary cardiac tumor, is rare. The clinical features of this tumor are principally intracardiac obstruction, extracardiac embolism, and general symptoms including fever, myalgia, arthralgia. Although cutaneous manifestations in patients with cardiac myxoma are frequent, in rare cases, cutaneous signs have been clues to the correct diagnosis. We report a 42-year-old male who presented with recurrent multiple purpuric patches on both palms and soles for 4 months. Histopathological finding showed a myxomatous embolus in the arteriole in the lower dermis. Echocardiogram demonstrated the presence of a left atrial myxoma with a provisional diagnosis of left atrial myxoma. In our patient, skin examinations and histopathological finding led us to the diagnosis of cardiac myxoma.